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Personal
Born: in Erfurt, Germany March 15th 1967
Citizenship: Germany
Current visa status: Permanent Resident Alien (Green card)

Education
Medical School, Friedrich-Schiller-University Jena, Germany (1990-93, 1994-96, MD)
Medical School, University of Newcastle upon Tyne, UK (1993-94, Medicine)
Fully licensed physician in Germany (since 10/98)
Doctor of Medicine doctor medicinae (like PhD), Friedrich-Schiller-University Jena, Germany (11/1999)

Professional Experience
Department of Human Genetics, Friedrich-Schiller-University Jena, Germany (1994-95)
Medical Center, Friedrich-Schiller-University Jena, Germany (1985-89 and1995-96)
Department of Medical Informatics, Statistics and Documentation, Friedrich-Schiller-University Jena, Gemany (1996-99)
Department of Traumatology, Hand- and Reconstructive Surgery, Medical Center Klinikum Erfurt GmbH, Germany (1997-98)
Department of Obstetrics and Gynecology, Bethanien Hospital Moers, Germany (1998-2000)
Cancer Center, University of California, San Diego, USA (4/2000-3/2001)
San Diego Supercomputer Center, University of California, San Diego, USA (4/2001 -3/2008)
caBIG Deployment Lead at the UCSD Moores Cancer Center (4/2008 - present)

Lectures and Presentations
Tutorial Introduction to Bioinformatics for IEEE San Diego (2003)
Lecture at UCSD Extension on Object-Oriented Perl (2002)
Lecture at UCSD Extension on Federated Database Systems, IBM's Discovery Link software package (2002)
Lecture at the San Diego Community College on Perl, DBI, CGI , MySQL (2001)
Presentation Development of the Protein Kinase Resource at the FASEB meeting on protein kinases in Snowmass, CO (2001)


Past Research Projects
PhosphoOntology - Ontology to model protein phosphorylation and dephosphorylation in the context of signaltransduction with the short-term goal to relate protein kinases in PKR and protein phosphatases in Phosphabase

Scientific advisor and codeveloper of Patentinformatics - an online resource on life science related patent information

Development of a comprehensive web accessible compendium of information on the protein kinase family of enzymes (Protein Kinase Resource (PKR), now hosted at Purdue University) that includes tools for structural and computational analyses as well as links to related information maintained by others. PKR aims to be the reference resource for protein kinase classification and nomenclature.

Collaboration with John Moreland (SDSC) to integrate the Molecular Biology Toolkit as graphical front-end to the protein kinase resource database permitting easy and intuitive information retrieval and annotation for protein kinase researchers

Member of the developers team of PlantsP online resource (Functional Genomics of Plant Phosphorylation)

Collaboration with IBM to built a federated data resource that allows easy access to important public data resources in lifescience research in relation database format. Thus alleviate the frequently redundant efforts by many research projects to extract the data from flatfiles or served html pages. This project also includes cross-communication with several other key projects at SDSC, such as the Alliance for Cellular Signaling (AfCS), the Protein Data Bank (PDB), the Encyclopedia of Life (EOL), the Joint Center for Structural Genomics (JCSG), and others.

Software development on Xserve (Apple) in evaluation of MacOS X server and LinuxPPC (Yellowdog) as a platform for Bioinformatics research and applications.

Collaboration with BIOGEM (Microarray facility of UCSD, Gary Hardiman, Richard Rouse) – Research on profiling gene expression using a noncompetitive two-color microarray assay by measuring hybridization stoichiometry. Building bioinformatics support, and an annotation and experiment database for the microarrays manufactured and/or processed by BIOGEM.

Moleculargenetic mechanisms of in vitro and in vivo resistance against the anticancer drug cisplatin in collaboration with Stephen Howell at the UCSD Cancer Center

Other activities
Referee for the Journal of Medicinal Chemistry.
Referee for the Bioinformatics Journal.
Referee for the FEBS Journal (European Journal of Biochemistry).
Conference coordinator and organizer of the international event PKR Protein Phosphorylation Workshop, held in December 2003 in Asilomar (Pacific Grove, CA).
Conference chair and scientific advisor of the 2005 CHI Protein Kinase Targets conference, Boston


Research Support
National Science Foundation (NSF) - NSF/DBI-0217951 (current funding)
Proctor & Gamble Funds (via Professor Lynn Ten Eyck at the SDSC) (4/2001-8/2002)
German Research Foundation (DFG) - Grant NI-602 (4/2000-3/2001)

Honors and Awards
3/2003 Award of Excellence from the San Diego Supercomputer Center (SDSC) for work on the Protein Kinase Resource (PKR)
4/2000-3/2001 Scholarship from the German Research Foundation (DFG)
1992-96 Fellow of the German National Academic Foundation (Supporting the leading one percent of all students in Germany)
1993-94 Scholarship from the German Academic Exchange Service (DAAD)
1-4/1997 Scholarship from the Friedrich-Schiller-University Jena